EuroMISE centrum – Cardio, co-holder organisation University of Economics, Prague

Analytic Questions

Introduction

STULONG data were analysed using basic statistic methods. The listed analytic questions, which have not been subjected to study yet, are related to various groups based on various aspects.

The first aspect is based on the patient observation methodology. It classifies patients in three basic groups:

  1. Normal Group (for attribute PUVSKUP there are codes 1 + 2)
  2. Risk Group (for attribute PUVSKUP there are codes 3 + 4)
  3. Pathologic Group (for attribute PUVSKUP there is code 5)

The second aspect of analysis is according to the new criteria of the value of risk factors of atherosclerosis and theirs interactions.

To solve analytic questions the following criteria are important:

Analytic questions may be divided into three groups:

 

Entry Examination

  1. What are the relations between social factors (see attribute group social characteristics) and the following characteristics of men in the respective groups:
    1. Physical activity at work and in free time (see group of attributes physical activity),
    2. Smoking (see group of attributes smoking),
    3. Alcohol consumption (see group of attributes alcohol),
    4. BMI (body mass index, BMI = weight in kg / (height in m)2 ) (see group of attributes physical examination),
    5. Blood pressure (see group of attributes physical examination),
    6. Level of overall cholesterol, HDL cholesterol, triglycerides (see group of attributes biochemical examination).

  2. What are the relations between physical activity at work and in free time ( see group of attributes physical examination) and the following characteristics of men in the respective groups:
    1. Smoking (see group of attributes smoking),
    2. Alcohol consumption (see group of attributes alcohol),
    3. BMI (body mass index, BMI = weight in kg / (height in m)2) (see group of attributes physical examination),
    4. Blood pressure (see group of attributes physical examination),
    5. Level of overall cholesterol, HDL cholesterol, triglycerides (see group of attributes biochemical examination).

  3. What are the relations between alcohol consumption (see group of attributes alcohol) and the following characteristics of men in the respective groups:
    1. Smoking (see group of attributes smoking),
    2. BMI (body mass index, BMI = weight in kg / (height in m)2) (see group of attributes physical examination),
    3. Blood pressure (see group of attributes physical examination),
    4. Level of overall cholesterol, HDL cholesterol, triglycerides (see group of attributes biochemical examination).

  4. Are there any differences between the respective groups (normal, risk and pathologic – see above) in the above stated relations?

 

Long-term Observation and Basic Patient Groups

  1. Are there any differences between men of the two risk subgroups (for attribute PUVSKUP it is RGI + RGC), who came down with the observed cardiovascular diseases in the course of 20 years and those who stayed healthy (the illness is based on attributes HODN1, ROK1, HODN2, ROK2, HODN3, ROK3, HODN11, ROK11, HODN12, ROK12, HODN13, ROK13, HODN14, ROK14, HODN21, ROK21, HODN23, ROK23, see the group of attributes questionnaire A2).

  2. Were there any differences between men of the risk group (for attribute PUVSKUP there are codes 3 + 4), who came down with the observed cardiovascular diseases and those who stayed healthy at the initial examination? We are interested in the following:
    1. Social factors (see group of attributes social characteristics),
    2. Physical activity at work and in free time (see group of attributes physical activity),
    3. Smoking (see group of attributes smoking),
    4. Alcohol consumption (see group of attributes alcohol),
    5. BMI (body mass index, BMI = weight in kg / (height in m)2) (see group of attributes physical examination),
    6. Blood pressure (see group of attributes physical examination),
    7. Cholesterol level (see group of attributes biochemical examination).

  3. Were there any differences between men of the risk group (for attribute PUVSKUP it is RSI + RSK), who came down with the observed cardiovascular diseases and those who stayed healthy in the development of risk factors and other characteristics?
    1. Change of job (see attribute ZMCHARZA – change of job type),
    2. Change of physical activity in the free time (see attribute ZMTELAKT – change of physical activity in the free time and attribute AKTPOZAM – current physical activity in the free time),
    3. Smoking (see attributes ZMKOUR – change of smoking and POCCIG – number of cigarettes a day),
    4. Diet (see attribute ZMDIET – change of diet compared to the previous period),
    5. BMI (body mass index, BMI = weight in kg / (height in m)2 (see attributes HEIGHT in the first examination and WEIGHT in the control examination),
    6. Blood pressure (see attributes SYST, DIAST, in control examinations),
    7. Level of lipids (see attributes CHLST, CHLSTMG, TRIGL, TRIGLMG, HDL, HDLMG, LDL see group of attributes biochemical examination),
    8. Glycaemia and lower level of uric acid (see attributes GLYKEMIE and KYSMOC),
    9. Combination of increased triglycerides level and lower HDL cholesterol,
    10. Combination of overweight and increased level of:
      1. overall cholesterol,
      2. LDL cholesterol,
      3. triglycerides.
    11. Combination of overweight and lower level of HDL cholesterol,
    12. Combination of smoking and increased level of:
      1. overall cholesterol,
      2. LDL cholesterol,
      3. triglycerides.
    13. Combination of smoking and lower level of HDL cholesterol.

  4. Is there a correlation between the skin folds and BMI in the particular basic groups of patients?

 

Long-term Observation and Groups Overweight-Pressure

These aspects divide patients into four groups called the overweight-pressure groups:

The following criteria are used to divide patients into the overweight-pressure groups:

It is important to know that these groups may change in the course of observation.

  1. Are these groups stable or does patient migration occur?
  2. What type of patient migration between the groups exists and which patients are subject to migration?
  3. Are there any differences between the groups with regards to lipids (cholesterol, HDL, triglycerides and LDL)?
  4. Are there any differences between the groups with regards to the combination of increased triglycerides + lower HDL cholesterol?
  5. Are any other differences between the groups related to factors (especially social characteristics, physical activity and smoking)?

Date: September 22, 2017

URL: